PDF 1 of 13, Salvia Divinorum Extraction Articles

"The second paragraph states "receptor binding studies have revealed nothing, which could indicate a previously unknown pathway in the brain." This is very wrong - there are many papers, and even a wikipedia article, that have found that Salvinorin A is an agonist for Kappa-opioid receptors. Morphine also stimulates this receptor (hence the name of the receptor) but morphine is not selective and stimulates the mu-opioid receptor making it addictive. Since Salvinorin-A doesn't work on the mu-opioid receptors its not addictive." --Ian, 11/21/06

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PDF needs to be opened Open this PDF (135KB) Salvia divinorum info and users guide.pdf Add Comment (1 total) "The second paragraph states "receptor binding studies have revealed nothing, which could indicate a previously unknown pathway in the brain." This is very wrong - there are many papers, and even a wikipedia article, that have found that Salvinorin A is an agonist for Kappa-opioid receptors. Morphine also stimulates this receptor (hence the name of the receptor) but morphine is not selective and stimulates the mu-opioid receptor making it addictive. Since Salvinorin-A doesn't work on the mu-opioid receptors its not addictive." --Ian, 11/21/06
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